The UFC middleweight and lightweight titles were on the line Saturday, October 14, 2006 at the Mandalay Bay Events Center in Las Vegas, Nevada. The 185-pound champion Rich Franklin defends his crown against Anderson Silva, and Sean Sherk and Kenny Florian battle to become just the second 155-pound champ in UFC history at UFC 64: Unstoppable.

Event Bout:UFC Middleweight Championship

* Rich Franklin (185) vs. Anderson Silva (185)

Event Bout: Vacant UFC Lightweight Championship

* Kenny Florian (155) vs. Sean Sherk (154.5)
* Jon Fitch (170) vs. Kuniyoshi Hironaka (170)
* Cheick Kongo (226) vs. Carmelo Marrero (222)
* Spencer Fisher (155) vs. Joe Lauzon (155)
* Keith Jardine (205) vs. Mike Nickels (205)
* Yushin Okami (185) vs. Kalib Starnes (185)
* Justin James (155) vs. Clay Guida (154.5)
* Kurt Pellegrino (154.5) vs. Junior Assuncao (155)